Tuesday, 13 November 2012

Pseudobulbar Affect?


Pseudobulbar Affect (PBA) - uncontrollable laughing and/or crying)

Approximately 10 percent of persons with MS experience uncontrollable episodes of laughing and/or crying that are unpredictable and seem to have little or no relationship to actual events or the person's emotions. A person may sob uncontrollably without feeling sad, or laugh inappropriately in a situation that isn't funny. These changes are thought to result from lesions—damaged areas—in emotional pathways in the brain. It is important for family members and caregivers to know this, and realize that people with MS may not always be able to control their emotions.   Several medications, including amitriptyline. levodopa, desipramine, fluoxetine, and fluvoxamine, have been used over the years to control PBA. In 2010, Nuedexta™ was approved by the US Food and Drug Administration (FDA) to treat pseudobulbar affect in MS and other neurologic disorders. This medication, which is taken by mouth once a day, is a combination of dextromethorphan and an enzyme inhibitor to sustain a therapeutic level of dextromethorphan in the body.

LoL. No wonder sometimes I cry unexpectedly.. LoL2.. ;)

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